Heroes of Progress, Pt. 33: Hitchings and Elion
Introducing George Hitchings and Gertrude Elion, two American scientists who pioneered the development of rational drug design. For most of history, the traditional method of drug discovery relied on a trial-and-error approach to determine the effectiveness of different treatments. Contrary to perceived wisdom, Hitchings and Elion’s new method of rational drug design focused on studying the differences between human cells and disease-causing pathogenic cells. From these findings, the method develops specifically-designed drugs to only target harmful pathogens.
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